Major stock markets in the Asia-Pacific region traded mixed on Wednesday as investors weighed the potential impact of tensions between Washington and Beijing against economies reopening and progress towards a COVID-19 vaccine. Stocks rose in Japan, Australia, and South Korea. Meanwhile, the Shanghai Composite and the Hang Seng index fell after the White House warned that Hong Kong could lose its status as a global financial center if China’s efforts to impose national security laws on the territory goes ahead.